Short Facts About Parenteral Nutrition | Clinical Nutrition LAM Initiative

Short Facts About Parenteral Nutrition

  • Enteral nutrition is sometimes not sufficient: Parenteral nutrition fills a critical gap- especially in ICU patients and after abdominal surgery.1
  • PN is safe when indicated, and when used appropriately.2,3
  • Early PN is as safe as enteral nutrition when administered appropriately.4
  • PN can help to improve patient outcomes.1,2,3,5
  • SPN reduces risk of hospital-acquired infections in ICU patients by 11% when compared to EN.1
  • Early PN has been shown to reduce treatment costs by USD 3,150 per patient.5
  • 1. a. b. c. Heidegger CP, Berger MM, Graf S et al. Optimisation of energy provision with supplemental parenteral nutrition in critically ill patients: a randomised controlled clinical trial. Lancet 2013;381(9864):385-393.
  • 2. a. b. Doig GS, Simpson F, Sweetman EA et al. Early parenteral nutrition in critically ill patients with short-term relative contraindications to early enteral nutrition: a randomized controlled trial. JAMA 2013;309(20):2130-2138.
  • 3. a. b. Thibault R, Heidegger CP, Berger MM et al. Parenteral nutrition in the intensive care unit: cautious use improves outcome. Swiss Med Wkly 2014;144:w13997.
  • 4. Harvey SE, Parrott F, Harrison DA et al. Trial of the route of early nutritional support in critically ill adults. N Engl J Med 2014;371(18):1673-1684.
  • 5. a. b. Doig GS, Simpson F, Early PN Trial Investigators Group, Study Management Committee Members Cooper DJ Davies AR. Early parenteral nutrition in critically ill patients with short-term relative contraindications to early enteral nutrition: a full economic analysis of a multicenter randomized controlled trial based on US costs. Clinicoecon Outcomes Res 2013;5:369-379.

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